Characterization of multidrug-resistant diabetic foot ulcer enterococci.
نویسندگان
چکیده
INTRODUCTION Diabetes mellitus is a highly prevalent chronic progressive disease with complications that include diabetic-foot ulcers. METHODS Enterococci isolated from diabetic-foot infections were identified, evaluated by macro-restriction analysis, and screened for virulence traits and antimicrobial resistance. RESULTS All isolates were considered multidrug-resistant, cytolysin and gelatinase producers, and the majority also demonstrated the ability to produce biofilms. CONCLUSIONS These results indicate the importance of enterococci in diabetic-foot infection development and persistence, especially regarding their biofilm-forming ability and resistance to clinically relevant antibiotics.
منابع مشابه
Identification and Characterization of a High Vancomycin-Resistant Staphylococcus aureus Harboring VanA Gene Cluster Isolated from Diabetic Foot Ulcer
Objective(s) Staphylococcus aureus is a common cause of human infection, and emergence of vancomycin-resistance S. aureus is a great concern for treatment of methicillin-resistant S. aureus,(MRSA) in recent years (MRSA). Here, we report the isolation of high-level VRSA. Materials and Methods S. aureus was isolated from foot ulcer of a diabetic woman in Tehran, Iran. Antibiotic susceptibilit...
متن کاملDetermination of the Resistance Pattern of Prevalent Aerobic Bacterial Infections of Diabetic Foot Ulcer
Background and Objective: Diabetes mellitus is one of the main problems in health systems in the world. Diabetic Foot infections (DFI) is one of the main complications and the most cause of non-traumatic lower limb amputation .This study aimed to determine the prevalence of bacteria involved in DFI and their antibiotic resistance in patients with DFI diagnosis. Patients and Metho...
متن کاملPrevalence of Microorganisms and Antibiotic Sensitivity Among Patients with Diabetic Foot Ulcer in Sulaimani City, Iraq
Background: Diabetic foot ulcers (DFUs) are responsible for days of costly hospitalization and are the major cause of medical lower limb amputations. Determining the appropriate antimicrobial therapy for DFUs is highly dependent on recognizing the microorganisms that cause them. Many reports have indicated that there has been a remarkable increase in antibiotic resistance.<br /...
متن کاملClinico-bacteriology and risk factors for the diabetic foot infection with multidrug resistant microorganisms in north India
This study was carried out in diabetic patients with foot ulcer, to determine the bacterial profile of infected ulcer, antibiotic resistance of the isolates and to find out the potential risk factors for infection with multidrug resistance. Gram-negative bacilli were screened for extended spectrum β lactamase (ESBL) production and Staphylococcus aureus were screened for methicillin resistance. ...
متن کاملUse of maggot therapy for treating a diabetic foot ulcer colonized by multidrug resistant bacteria in Brazil
This study reports the efficacy of maggot therapy in the treatment of diabetic foot ulcer infected with multidrug resistant microorganisms. A 74 year old female patient with diabetes for over 30 years, was treated with maggot therapy using larvae of Chrysomya megacephala. The microbiological samples were collected to evaluate aetiology of the infection. The therapy done for 43 days resulted in ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Enfermedades infecciosas y microbiologia clinica
دوره 34 2 شماره
صفحات -
تاریخ انتشار 2016